Sandeep Nathan, MD, MS

Associate Professor of Medicine
Director, Interventional Cardiology Fellowship Program
Co-Director, Cardiac Catheterization Laboratory


Dr. Sandeep Nathan is a highly skilled cardiologist who specializes in interventional cardiovascular procedures. Dr. Nathan performs a wide range of coronary and peripheral vascular procedures for the diagnosis and treatment of cardiovascular disease, including balloon angioplasty, stenting, atherectomy, thrombectomy, cryoplasty and intravascular ultrasound imaging.

He is one of few interventional cardiologists who routinely perform transradial angiography and intervention, a less invasive alternative to traditional approaches. Transradial angiography uses an artery in the wrist, instead of the leg, as the entryway for diagnostic imaging and therapeutic procedures, such as angioplasty and stenting. This technique offers fewer risks and greater advantages, including increased patient comfort and immediate mobility following the procedure. Additionally, Dr. Nathan is a general cardiologist who treats patients with coronary artery disease (CAD), peripheral arterial disease (PAD) and risk factors for heart disease.

His research interests include platelet biology, interventional device therapies, intravascular imaging, and the use of antiplatelet and antithrombotic therapies (blood thinners) in the management of acute coronary syndromes and heart attacks. Dr. Nathan holds a master's degree in clinical research. He currently serves as a principal investigator or co-investigator on several clinical trials evaluating: new antiplatelet therapies in patients with acute coronary syndromes; novel stents for the treatment of coronary artery disease; and clinical outcomes in patients who have had percutaneous coronary interventions (angioplasty/stent) and heart attacks.

Practice Location

Duchossois Center for Advanced Medicine 
5758 S. Maryland Avenue 
Chicago, IL 60637

Year Started Practice


Board Certifications

Internal Medicine 
Cardiovascular Disease 
Interventional Cardiology

Medical School

Boston University School of Medicine


University of Pittsburgh Medical Center


Rush University Medical Center, Chicago


American College of Cardiology 
Society for Cardiovascular Angiography and Intervention

Languages Spoken



Office Phone

(773) 702-2697

Office Fax

(773) 702-0241

Office Postal Address

Sandeep Nathan, MD, MS 
The University of Chicago Medicine 
5841 S. Maryland Avenue, MC 5076 
Chicago, IL 60637

Related Videos

Transradial approach for cardiac catheterization:  The new frontier of coronary intervention Video

Transradial approach for cardiac catheterization: The new frontier of coronary intervention

The transradial (TR) approach for cardiac catheterization utilizes the superficial artery of the wrist and offers significant advantages over the femoral approach by way of reductions in major bleeding, vascular complications and length of stay