Mayo Clinic and collaborators find new class of drugs that reduces aging in mice

James L. Kirkland, M.D., Ph.D., head of the Mayo Clinic Robert and Arlene Kogod Center on Aging, discusses a study finding a new class of drugs, identified and validated by Mayo Clinic researchers and their collaborators, clearly reduces health problems in mice by limiting the effect of senescent cells — the cells that cause frailty and contribute to diseases associated with age. The researchers say this is a first step toward developing similar treatments for aging patients. Their findings appear in the journal Aging Cell.

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