The Neurobiology of Depression [Psychiatry]

We know what depression looks like on the outside, in terms of a patient’s behavior, but our medical understanding of the actual progression of the disease and its treatments continues to evolve.  “There are clear differences between a healthy brain and a depressed brain,” says Rachel Katz, MD, a Yale Assistant Professor of Clinical Psychiatry. “The exciting thing is, when you treat that depression effectively, the brain goes back to looking like a healthy brain.”  In this video, Dr. Katz joins John Krystal, MD, chair of Yale’s Department of Psychiatry, in explaining how depression manifests in the brain. 

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John Krystal, MD.

John Krystal, MD

Chair, Department of Psychiatry

John Krystal, MD, is a leading expert in the areas of alcoholism, post-traumatic stress disorder, schizophrenia, and depression. His work links psychopharmacology, neuroimaging, molecular genetics, and computational neuroscience to study ...

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