Early Detection of Mesothelioma

Anil Vachani, MD, Director of Clinical Research for Penn Interventional Pulmonary Services, outlines the challenges inherent in the early detection of mesothelioma, a disease that may be asymptomatic for decades before the first symptoms appear. Dr. Vachani reviews the current diagnostic armamentarium, including the blood tests (serum mesothelin, plasma osteopontin, fibulin­3 and HMGB1) and screening tools (serum mesothelin), concluding with a discussion of mesothelioma studies in the Philadelphia region.