Researchers urge caution in interpreting joint replacement predictors, noting that surgery reflects access and decision-making as well as disease biology.
Severe social jet lag among surgeons was associated with higher rates of major adverse events, independent of sleep duration, workload, and patient risk.
In a UK cohort, patients with osteoarthritis who initiated centrally acting analgesics had a higher hazard of knee or hip replacement than those who initiated SSRIs, though residual confounding by pain severity remains a key limitation.
Conexiant
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Swedish registry analysis linked surgical treatment with better patient-reported function in comminuted intra-articular distal radius fractures, while other fracture patterns showed limited benefit.
Patients with preoperative vitamin D deficiency had higher postoperative pain scores and opioid use after mastectomy, including more than triple the odds of moderate to severe pain within 24 hours of surgery.