Mount Sinai Neurosurgery Chair, Joshua Bederson, MD Case Study: Brain Tumor Embolization

Mount Sinai increasingly is turning to embolization to help remove skull base tumors such as meningiomas more completely, selectively, and safely. Using a strategy devised by its biomedical incubator, Mount Sinai BioDesign, surgeons can now assess and quantify the extent of embolization through an analysis of an additional MRI sequence following embolization and preceding surgical resection.

Leading this effort is Joshua B. Bederson, MD, the Leonard I. Malis, MD / Corinne and Joseph Graber Professor of Neurosurgery, and Chair of Neurosurgery for the Mount Sinai Health System. “Not all skull base tumors are appropriate for embolization, and it does have a low level of risk,” says Dr. Bederson, “but for those challenging cases where large, highly vascular tumors are fed by dedicated arteries, the procedure can be particularly useful.”

In a narrated video, Dr. Bederson demonstrates how preoperative endovascular embolization can be an effective—and safe—approach in the case of a 24-year-old male with a large left parasagittal meningioma who complained of right lower extremity weakness, new onset of fatigue, and bilateral hand weakness.

“At surgery, we found that the tumor was soft and almost completely devascularized from the preoperative embolization, reducing the amount of viable tumor encountered at surgery,” says Dr. Bederson. “This young man did extremely well and noticed an improvement in motor function immediately after surgery.”

Featured Faculty

Joshua B. Bederson, MD

The Leonard I. Malis, MD / Corinne and Joseph Graber Professor of Neurosurgery
Chair of Neurosurgery for the Mount Sinai Health System
Founder, Mount Sinai BioDesign

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